Cistitis eosinofílica en mujer con enfermedad renal crónica
Palabras clave:
cistitis, eosinofilia, hematuria, disuria
Resumen
Se presenta caso de una mujer de 70 años, con antecedentes de enfermedad renal crónica sin requerimiento dialítico que ingresa con descompensación aguda y que mejora con sesiones de hemodiálisis. Al examen físico llama la atención hematuria franca por lo que se solicita ecografía de pelvis donde aprecia vejiga distendida con coágulo en su interior de 7,2 cm. La tomografía muestra aparente tumor de pared de vejiga. La uretrocistografía confirma una cistitis crónica eosinofílica. Es manejada con hidroxicina teniendo respuesta favorable cediendo episodios de hematuria. La cistitis eosinofílica es una condición médica rara que se presenta con síntomas urinarios tales como disuria y hematuria. Es más común en niños que en adultos. El método diagnóstico es a través de una biopsia de pared vesical por cistoscopía. El manejo está dirigido a aliviar los síntomas. El interés por el caso se debe a la rareza de esta patología.
Citas
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2. Adeleye O, Trickett JS, Wright BL, Khan A. Refractory eosinophilic cystitis controlled with low-dose cyclosporine therapy: A case report. Urol Case Rep [Internet]. 2021 [cited 2023 Enero 29];39:101829. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8424508. doi: 10.1016/j.eucr.2021.101829
3. Lopez-Beltran A, Young RH. Nonneoplastic disorders of the urinary bladder. In: MacLennan GT, Bostwick DG, Cheng L, (Editor). Urologic surgical pathology. 4th Edition. Philadelphia Elsevier; 2020: 195-229. doi: https://doi.org/10.1016/B978-0-323-54941-7.00005-0
4. Manach Q, Drouin SJ, Vieillefond A, Rouprêt M. Cistitis crónicas no bacterianas. EMC - Urol. 2018; 50(1):1–12
5. van den Ouden D, van Kaam N, Eland D. Eosinophilic cystitis presenting as urinary retention. Urol Int. 2001;66(1):22–6
6. Aláez-Chillarón AB, Pérez-Merino E, Kilmurray L, Martín-Vieira FJ, Mojtar F, Moreno-Manso I. Enteritis eosinofílica, una causa poco frecuente de intervención quirúrgica urgente. Gastroenterol Hepatol [Internet]. 2014 [citado 29 Enero 2023];37(6):354–61. Disponible en: https://www.elsevier.es/es-revista-gastroenterologia-hepatologia-14-articulo-enteritis-eosinofilica-una-causa-poco-S0210570513002628. doi: 10.1016/j.gastrohep.2013.10.006
7. Meria P, Jungers P. Pyélite incrustante : un diagnostic précoce facilite la prise en charge conservatrice. Presse Médicale. 2008; 37(1. Part 2):85–7
8. Johnson MH, Strope SA. Encrusted cystitis. Urology [Internet]. 2012 [citado 29 Enero 2023];79(3):e31–2. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3294293. doi: 10.1016/j.urology.2011.12.013
9. Cooke WD, Cooke AJT. Successful treatment of eosinophilic cystitis with benralizumab. Urol Case Rep [Internet]. 2020 [cited 2023 Jan 29]; 33:101379. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7574143. doi: 10.1016/j.eucr.2020.101379
10.Saadi A, Bouzouita A, Ayed H, Kerkeni W, Cherif M, Ben Slama RM, et al. Pseudotumoral eosinophilic cystitis. Urol Case Rep [Internet]. 2015 [cited 2023 Jan 29];3(3):65–7. Available from: https://www.sciencedirect.com/science/article/pii/S2214442015000078. doi: https://doi.org/10.1016/j.eucr.2015.01.006
11.Rossi E, Pavanello P, Marzola A, Franchella A. Eosinophilic cystitis and nephrogenic adenoma of the bladder: a rare association of 2 unusual findings in childhood. J Pediatr Surg [Internet]. 2011 [cited 2023 Jan 29];46(4):e31–4. Available from: https://www.jpedsurg.org/article/S0022-3468(11)00047-9/fulltext. doi: https://doi.org/10.1016/j.jpedsurg.2010.12.027
12.Chia D. Eosinophilic cystitis and haematuria: Case report of a rare disease and common presentation. Int J Surg Case Rep [Internet]. 2016 [cited 2023 Jan 29]; 24:43–5. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4873027. doi: 10.1016/j.ijscr.2016.04.055
13.Klion AD. How I treat hypereosinophilic syndromes. Blood [Internet]. 2015 [cited 2023 Jan 29];126(9):1069–77. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4551360. doi: 10.1182/blood-2014-11-551614
14.Aleem S, Kumar B, Fasano MB, Takacs E, Azar AE. Successful use of cyclosporine as treatment for eosinophilic cystitis: a case report. World Allergy Organ J [Internet]. 2016 [cited 2023 Jan 29]; 9:22. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4939020. doi: 10.1186/s40413-016-0113-4
15.Dixit Ch, Bullock T, Kahle L, Warrier M. Use of benralizumab in refractory eosinophilic cystitis improves symptoms and reduces bladder eosinophils. [Resumen] J Allergy Clin Immunol [Internet]. 2021 [cited 2023 Jan 29];147(2): AB64. Available from: https://www.jacionline.org/article/S0091-6749(20)32017-0/fulltext
