Disfunción tiroidea en pacientes con diabetes mellitus tipo 2 ¿Una asociación frecuente?
Resumen
Introducción: la disfunción tiroidea (DT) se observa con frecuencia en pacientes con diabetes mellitus tipo 2 (DM2) siendo el hipotiroidismo es el más frecuente.
Objetivos: determinar frecuencia de DT en pacientes con DM2, que consultan en la Primera Cátedra de Clínica Médica del Hospital de Clínicas (San Lorenzo, Paraguay), de enero a diciembre del 2013.
Material y Métodos: diseño observacional, retrospectivo, analítico. Incluimos pacientes de ambos sexos, mayores de 18 años. Excluimos pacientes con fármacos que afecten función tiroidea, tiroidectomizados, enfermos renales crónicos.
Resultados: incluimos 254 pacientes, encontramos DT en 9,45% (n 24), diagnóstico previo 8,26% (n 21) y nuevos casos 1,18 % (n 3). Presentaron hipotiroidismo 66,7 % (n 16), siendo hipotiroidismo clínico 41,6% (n 10) e hipotiroidismo subclínico 25% (n 6). Hallamos hipertiroidismo en 33,3 (n 8), siendo hipertiroidismo clínico 20,8% (n 5) e hipertiroidismo subclínico 12,5% (n 3). De los 254 pacientes, 179 fueron mujeres (22 con DT) y 97 varones (2 con DT), [OR 6,6 (1,5-28,9) p 0,003]; 126 eran mayores de 50 años (17 con DT) y 128 eran ≤ 50 años (7 con DT): [OR 2,6 (1,1-6,7) p 0,03].
Conclusiones: la frecuencia de DT en pacientes con DM2 fue 9,45%, con predominio en mujeres y mayores de 50 años, siendo más frecuente el hipotiroidismo clínico.
Citas
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